Pseudo-Epidemic Clostridium difficile and Laxative Use

Clostridium difficile: the emerging epidemic.

Epidemic Clostridium difficile Ribotype 027 in Chile

was found to be slightly different from other HEVs and included a putative ORF (ORF4) of 552 nt that overlapped with ORF1 (online Technical Appendix Figure). A similar pattern of genome organization was observed for both FRHEVs. Phylogenetic analysis of the complete genomes clearly showed that FRHEV was separated from genotype 1–4 HEVs and clustered with rat HEV (Figure). Similar phylogenetic c...

Fluoroquinolone Use and Clostridium difficile–Associated Diarrhea

We performed a case-control study to evaluate the association between antibiotic use and Clostridium difficile-associated diarrhea (CDAD), matching for admission unit and time at risk for CDAD. A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confidence interval 2.6 to 61.6) was the strongest risk factor for CDAD.

Epidemic Clostridium difficile Strain in Hospital Visitation Dog

5. Hepatic granuloma due to a nymph of Linguatula serrata in a woman from Michigan: a case report and review of the literature. Am J Trop Med Hyg. 1984;33:187–9. 6. A nodular pulmonary lesion due to Linguatula serrata in an HIV-positive man. Two cases of human infestation by larvae of Linguatula serrata. To the Editor: Rates of illness and death from Clostridium difficile–asso-ciated disease (C...

First Australian isolation of epidemic Clostridium difficile PCR ribotype 027.

We report the first isolation in Australia of a hypervirulent epidemic strain of Clostridium difficile, PCR ribotype 027. It was isolated from a 43-year-old woman with a permanent ileostomy, who appears to have been infected while travelling in the United States. The isolate was positive for toxin A, toxin B and binary toxin, and resistant to fluoroquinolone antimicrobials, and had characterist...